Differin
A true prescription-strength retinoid, available over the counter, and the best value in acne care.
Adapalene was prescription-only until 2016. It targets the receptors most involved in acne, which makes it more effective for breakouts than retinol and, for many people, less irritating. Expect a purge between weeks two and six — that is the treatment working, not failing.
How to use it: Your active step. One new active at a time.
Compared across every retailer we track, with per-unit pricing so different sizes are judged fairly.
Save $1.55 by buying from Walmart rather than the most expensive stockist.
| Retailer | Price | Per unit | Shipping | Link |
|---|---|---|---|---|
WalmartCheapest Checked 2 months ago | $13.80−8% $14.99 | $0.31 / g | $6.99, free over $35 | Visit ↗ |
Amazon Checked 2 months ago | $13.95−20% $17.45 | $0.31 / g | Free | Visit ↗ |
Target Checked 2 months ago | $14.10−6% $14.99 | $0.31 / g | $5.99, free over $35 | Visit ↗ |
Dermstore Checked 2 months ago | $15.25−20% $19.05 | $0.34 / g | $4.95, free over $50 |
Prices shown are curated sample data, not a live feed — treat them as illustrative and confirm on the retailer’s own site before buying. skinfrndly earns nothing from these links.
1 key active doing the work here.
skinfrndly is educational and is not medical advice. Recommendations are generated from the answers you gave and general dermatological guidance — they cannot account for your full history. For persistent or severe skin conditions, or before starting anything new during pregnancy, speak to a doctor or dermatologist.
| Visit ↗ |
Ulta Beauty Checked 2 months ago | $15.35 | $0.34 / g | $5.95, free over $35 | Visit ↗ |